Table 1.
Participant characteristics in evaluation and validation cohorts.
| Variables | Evaluation cohort (n = 324) | Validation cohort (n = 136) | P-value |
|---|---|---|---|
| Age (years) | 62.60 ± 12.00 | 63.73 ± 11.70 | 0.3537 |
| Male, n (%) | 250 (77.16%) | 103 (75.74%) | 0.7425 |
| Killip's classification > I, n (%) | 92 (28.40%) | 20 (14.71%) | 0.0018 |
| Diabetes mellitus, n (%) | 99 (30.56%) | 49 (36.03%) | 0.2523 |
| Hypertension, n (%) | 195 (60.19%) | 69 (50.74%) | 0.0617 |
| Myocardial infarction history, n (%) | 37 (11.42%) | 18 (13.24%) | 0.5834 |
| Anterior wall myocardial infarction, n (%) | 160 (49.38%) | 69 (50.74%) | 0.7903 |
| Apelin-12 (ng/mL) | 0.82 ± 0.33 | 0.84 ± 0.35 | 0.5605 |
| Apelin-12 change rate (%) | 13.74 ± 8.98 | 12.94 ± 8.63 | 0.3783 |
| SBP(mmHg) | 131.34 ± 27.20 | 133.13 ± 27.10 | 0.5194 |
| Albumin (g/L) | 37.95 ± 3.92 | 37.87 ± 3.64 | 0.8385 |
| Haemoglobin (g/L) | 143.46 ± 17.39 | 144.65 ± 16.79 | 0.499 |
| Total cholesterol (mmol/L) | 5.67 ± 1.11 | 5.65 ± 1.06 | 0.8583 |
| Triglyceride (mmol/L) | 1.09 ± 0.85 | 1.16 ± 0.82 | 0.4159 |
| High-density lipoprotein-C (mmol/L) | 1.19 ± 0.27 | 1.24 ± 0.26 | 0.0676 |
| Low-density lipoprotein-C (mmol/L) | 3.06 ± 0.71 | 3.00 ± 0.76 | 0.4184 |
| Fasting blood glucose (mmol/L) | 7.63 ± 2.52 | 7.76 ± 2.57 | 0.6159 |
| White blood cells × 109/L | 9.95 ± 3.72 | 10.40 ± 3.44 | 0.2269 |
| Heart rate | 77.54 ± 16.97 | 75.42 ± 17.56 | 0.2268 |
| Neutrophil (%) | 75.2 ± 11.71 | 76.89 ± 11.03 | 0.1515 |
| Creatinine (mmol/L) | 75.40 ± 25.20 | 72.91 ± 15.58 | 0.2855 |
| Uric acid (mmol/L) | 339.19 ± 75.20 | 332.5 ± 70.63 | 0.376 |
| Platelet × 109/L | 232.59 ± 56.05 | 231.14 ± 57.02 | 0.8012 |
| Blood urea nitrogen (mmol/L) | 6.66 ± 2.05 | 6.89 ± 2.12 | 0.2776 |
| Peak creatine kinase MB (U/L) | 126.83 ± 91.26 | 130.85 ± 85.75 | 0.661 |
| Peak cTnI (ng/ML) | 16.66 ± 12.87 | 16.47 ± 12.86 | 0.8852 |
| Pathological Q wave, n (%) | 154 (47.53%) | 67 (49.26%) | 0.735 |
| GENSINI score | 72.92 ± 32.17 | 70.18 ± 32.18 | 0.405 |
| Left atrial diameter (mm) | 37.53 ± 5.59 | 37.17 ± 5.90 | 0.5356 |
| Left ventricular diastolic diameter (mm) | 50.36 ± 6.24 | 50.51 ± 6.36 | 0.8151 |