Figure 5.

Effect of Cordia vignei leaf extract on SOD, CAT, and MDA on the colons of acetic acid-challenged rats. Rats (n = 5) orally received normal saline (10 ml kg⁻¹), sulfasalazine (500 mg kg⁻¹), or CVE (30-300 mg kg⁻¹) daily for 7 days. On day 4, rats were challenged with 500 μl acetic acid (4% v/v). Rats were sacrificed on day 8 and the colons were homogenized and centrifuged. The supernatant was used for the assay of activity of SOD (a) and CAT (b) and levels of MDA (c). Results were presented as mean ± SEM and statistically compared using student's t test. ^####P < 0.0001;^###P < 0.001;^##P < 0.01 (acetic acid control vs. naïve control); ^∗P < 0.05; ^∗∗P, <0.01, ^∗∗∗P < 0.001 (acetic acid control vs. treatment group).