Figure 6.

Effect of Cordia vignei leaf extract on serum levels of TNF-α and IL-6 in acetic acid-challenged rats. Rats (n = 5) were orally treated with normal saline (10 ml kg⁻¹), sulfasalazine (500 mg kg⁻¹), or CVE (30-300 mg kg⁻¹) daily for 7 days. On day 4, rats were challenged with 500 μl of acetic acid (4% v/v). Rats were sacrificed on day 8 and serum levels of TNF-α (a) and IL-6 (b) were assessed by ELISA. Results were presented as mean ± SEM. ^###P < 0.001 (acetic acid control vs. naïve control); ^∗P < 0.05, ^∗∗P < 0.01 (acetic acid control vs. treatment group).