| Population | Older adults (mean age of 50 years and above) free of cognitive impairment at baseline |
| Interventions | Anticholinergic burden as measured by any validated ordinal anticholinergic burden scale |
| Comparators (covariates of interest) | Age, sex, and comorbidity |
| Outcomes | Incident dementia or cognitive function (multidomain) |
| Type of study | Longitudinal, observational cohort/case‐control |
| Timing and setting | Recruitment from primary, secondary, or community settings Minimum of 1‐year follow‐up |
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