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. 2020 Jan 16;12(1):e6679. doi: 10.7759/cureus.6679

Table 1. Characteristics of advanced stage (III, IVA & IVB) hypopharyngeal cancer.

*ChemoRT = definitive chemoradiation therapy; RT = radiation therapy

  All Patients Definitive ChemoRT Surgery p-value
  (n = 103) n = 72 (69.9%) n = 31 (30.1%)  
Age, Mean (SD) 60.3 (9.3) 59.7 (9.5) 61.2 (8.8) 0.508
Gender/ Sex        
Male 92 (89.3%) 64 (89.9%) 28 (90.3%) 0.829
Female 11 (10.7%) 8 (11.1%) 3 (9.7%)  
Ethnicity        
Caucasians 39 (37.9%) 28 (38.9%) 11 (35.5%) 0.945
African Americans 61 (59.2%) 42 (58.3%) 19 (61.3%  
Others 3 (2.9%) 2 (2.8%) 1 (3.2%)  
Smoking status       0.035
Smoker 80 (77.7%) 60 (83.3%) 20 (64.5%)  
Non-Smoker 23 (22.3%) 12 (16.7%) 11 (35.5%)  
Alcohol Status       0.98
Drinker 60 (58.3%) 42 (58.3%) 18 (58.1%)  
Non- Drinker 43 (41.7%) 30 (41.7%) 13 (41.9%)  
TNM Stage (III, IV)        
T classification       0.024
T1 8 (7.8%) 5 (6.9%) 3 (9.7%)  
T2 13 (12.6%) 12 (16.7%) 1 (3.2%)  
T3 17 (16.5%) 8 (11.1%) 9 (29.0%)  
T4 41 (39.8%) 33 (45.8%) 8 (25.8%)  
Unknown 24 (23.3%) 14 (19.4%) 10 (32.3%)  
N Classification       0.116
N0 20 (19.4%) 12 (16.7%) 8 (25.8%)  
N1 8 (7.8%) 7 (9.7%) 1 (3.2%)  
N2 45 (43.7%) 34 (47.2%) 11 (35.5%)  
N3 9 (8.7%) 8 (11.1%) 1 (3.2%)  
Unknown 21 (20.4%) 11 (15.3%) 10 (32.3%)  
Sub-site       0.057
Pyriform Sinus 75 (72.8%) 51 (70.8%) 24 (77.4%)  
Post-pharyngeal Wall 10 (9.7%) 10 (13.9%) 0 (0.0%)  
Post-Cricoid 5 (4.9%) 3 (4.2%) 2 (6.5%)  
Hypopharynx Unknown 13 (12.3%) 8 (11.2 %) 5 (16.1 %)