Table 1. Characteristics of advanced stage (III, IVA & IVB) hypopharyngeal cancer.
All Patients | Definitive ChemoRT | Surgery | p-value | |
(n = 103) | n = 72 (69.9%) | n = 31 (30.1%) | ||
Age, Mean (SD) | 60.3 (9.3) | 59.7 (9.5) | 61.2 (8.8) | 0.508 |
Gender/ Sex | ||||
Male | 92 (89.3%) | 64 (89.9%) | 28 (90.3%) | 0.829 |
Female | 11 (10.7%) | 8 (11.1%) | 3 (9.7%) | |
Ethnicity | ||||
Caucasians | 39 (37.9%) | 28 (38.9%) | 11 (35.5%) | 0.945 |
African Americans | 61 (59.2%) | 42 (58.3%) | 19 (61.3% | |
Others | 3 (2.9%) | 2 (2.8%) | 1 (3.2%) | |
Smoking status | 0.035 | |||
Smoker | 80 (77.7%) | 60 (83.3%) | 20 (64.5%) | |
Non-Smoker | 23 (22.3%) | 12 (16.7%) | 11 (35.5%) | |
Alcohol Status | 0.98 | |||
Drinker | 60 (58.3%) | 42 (58.3%) | 18 (58.1%) | |
Non- Drinker | 43 (41.7%) | 30 (41.7%) | 13 (41.9%) | |
TNM Stage (III, IV) | ||||
T classification | 0.024 | |||
T1 | 8 (7.8%) | 5 (6.9%) | 3 (9.7%) | |
T2 | 13 (12.6%) | 12 (16.7%) | 1 (3.2%) | |
T3 | 17 (16.5%) | 8 (11.1%) | 9 (29.0%) | |
T4 | 41 (39.8%) | 33 (45.8%) | 8 (25.8%) | |
Unknown | 24 (23.3%) | 14 (19.4%) | 10 (32.3%) | |
N Classification | 0.116 | |||
N0 | 20 (19.4%) | 12 (16.7%) | 8 (25.8%) | |
N1 | 8 (7.8%) | 7 (9.7%) | 1 (3.2%) | |
N2 | 45 (43.7%) | 34 (47.2%) | 11 (35.5%) | |
N3 | 9 (8.7%) | 8 (11.1%) | 1 (3.2%) | |
Unknown | 21 (20.4%) | 11 (15.3%) | 10 (32.3%) | |
Sub-site | 0.057 | |||
Pyriform Sinus | 75 (72.8%) | 51 (70.8%) | 24 (77.4%) | |
Post-pharyngeal Wall | 10 (9.7%) | 10 (13.9%) | 0 (0.0%) | |
Post-Cricoid | 5 (4.9%) | 3 (4.2%) | 2 (6.5%) | |
Hypopharynx Unknown | 13 (12.3%) | 8 (11.2 %) | 5 (16.1 %) |