Fig. 1.
Body weight and splenomegaly following oral infection with C. burnetii in immunocompetent BALB/c mice. Mice were infected with 106 of either NM (•), CM-SC1 (■) or GP-CO1 (▲) via (a) OG or (b) IP. Sterile PBS (○) was delivered via OG as negative controls. Data are presented as the mean percentage change in weight relative to day 0 ± S.E.M. (c) Spleen-to-body weight (mean ± S.E.M.) is shown for mice infected with NM (black), CM-SC1 (dark grey), GP-CO1 (light grey) or PBS (white) via OG or IP. *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001 as determined by Student's t-test relative to PBS OG negative controls.