Fig. 6.

Mechanism of LNC internalization by BMDM and MG. Box plots show the range of DiD⁺ cells among BMDM a and MG b in 3 independent experiments. Cells from GBM tissue were incubated with 100 µg/ml colchicine, 10 µg/ml cytochalasin B, 50 µM LY294002, 100 nM Wortmannin, 100 U/ml Nystatin, DiD-loaded LNCs were added at 50 ng/ml DiD over-night and LNC internalization was analyzed by flow cytometry. Student t-test was performed, *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001