Skip to main content
. 2020 Feb 17;24:55. doi: 10.1186/s13054-020-2763-4

Fig. 2.

Fig. 2

Meropenem plasma and ELF concentration-time profiles. Meropenem plasma and ELF concentration time profiles of patients receiving a loading dose of 2000 mg i.v followed by a maintenance dose of 1 g q8h and 2 g q8h i.v. Intensive sampling was performed after the second day of treatment. A statistically significant difference was observed in plasma concentrations at any time points between the two groups (meropenem plasma concentrations of 12.9 (8.4) vs 23.0 (12.8) at pre-dose; 13.4 (7.3) vs 23.9 (16.7) at 1.5 h; 13.3 (8.3) vs 21.4 (15.5) at 3 h; 11.7 (8.2) vs 22.4 (15.3) at 6 h, and 12.3 (9.1) vs 18.9 (17.4) at 8 h, in the 1 g/8 h and 2 g/8 h groups, respectively).