Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Median (IQR) average AUC48–72 h in the plasma and ELF in the two dose groups estimated using the Bayesian posterior parametric estimates for each patient
| 1 g/8 h group (N = 16) | 2 g/8 h group (N = 15) | P | |
|---|---|---|---|
| AUC0–24 in the plasma (mg h/L) | 322.7 (225.6) | 492.3 (354.1) | 0.004 |
| AUC0–24 in ELF (mg h/L) | 101.5 (78.7) | 175.9 (258.7) | 0.047 |
| Ratio AUCELF/AUCplasma (%) | 31.8 (33.9) | 36.4 (44.4) | > 0.999 |
