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. 2020 Feb 18;12:30. doi: 10.1186/s13148-020-00826-4

Fig. 5.

Fig. 5

Histone methylation participates in diabetic angiopathy. Histone demethylase LSD1 and histone methyltransferases SET7, MLL, and Suv39h1 play critical roles in regulating vascular inflammatory response associated to diabetes mellitus. Jmjd1A and EZH2 are involved in VSMC proliferation, migration, or apoptosis respectively