Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 7;19(3):1641–1648. doi: 10.3892/etm.2020.8426

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Luo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 2. — Effect of downregulation of XIST on glioma cell proliferation and metastasis. (A) Following transfection with sh-XIST, XIST was significantly downregulated. The transfection of sh-XIST further potentiated miR-133a in U251 cells. (B) Cell viability of U251 lines following sh-XIST transfection. (C) Cell migration (magnification, ×16) and (D) cell invasion assay of glioma cells (magnification, ×100). (E) Western blot results demonstrated the expression levels of E-cadherin N-cadherin, α-catenin and vimentin in glioma cells following sh-XIST transfection. (F) Expression levels of SOX4 transcription factor. n=3, *P<0.05, **P<0.01 and ***P<0.001 vs. sh-NC. XIST, X-inactive specific transcript; sh, small hairpin RNA; miR, microRNA; SOX, SRY-box; NC, negative control; OD, optical density.