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. 2020 Feb 17;21:57. doi: 10.1186/s12859-020-3398-9

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Plots of M_s,cons versus M_s,int for all protein-RNA complexes according to the three conserved residue definitions of gradually more stringent levels: the conserved residue with sequence entropy lower than the average value (<s > _int) of the interface where it occurs (a), lower than half of the average value (<s > _int/2) (b), and equal to 0.0, namely, the fully conserved residue (c), respectively