Table 2.
Tobit Regression on EQ-5D-5L Index Score.
Excluding Recurrent VTE /Bleeding Event (n = 1695, obs = 5638) | Including Recurrent VTE /Bleeding Event (n = 1695, obs = 5365) | |||||||
---|---|---|---|---|---|---|---|---|
Coefficient | Standard Error | P > z | 95% Confidence Interval | Coefficient | Standard Error | P > z | 95% Confidence Interval | |
Patient without active cancer | ||||||||
Constant | 0.982 | 0.036 | 0 | 0.911 to 1.052 | 0.987 | 0.036 | 0 | 0.916 to 1.058 |
Age | −0.001 | 0.000 | .009 | −0.002 to 0.000 | −0.001 | 0.000 | .007 | −0.002 to 0.000 |
Male | 0.082 | 0.011 | 0 | 0.061 to 0.103 | 0.080 | 0.011 | 0 | 0.059 to 0.102 |
BMI | −0.003 | 0.001 | .009 | −0.005 to −0.001 | −0.003 | 0.001 | .009 | −0.005 to −0.001 |
Previous stroke | −0.098 | 0.038 | .011 | −0.173 to −0.022 | −0.099 | 0.039 | .011 | −0.175 to −0.023 |
Previous bleed events | −0.070 | 0.030 | .019 | −0.129 to −0.011 | −0.071 | 0.030 | .02 | −0.130 to −0.011 |
Prolonged immobilization | −0.036 | 0.017 | .031 | −0.068 to −0.003 | −0.034 | 0.017 | .04 | −0.067 to −0.002 |
>5 days in bed | −0.104 | 0.021 | 0 | −0.145 to −0.063 | −0.100 | 0.021 | 0 | −0.142 to −0.059 |
Lower extremity paralysis | −0.227 | 0.052 | 0 | −0.330 to −0.124 | −0.229 | 0.053 | 0 | −0.332 to −0.125 |
Congestive heart failure | −0.114 | 0.034 | .001 | −0.181 to −0.048 | −0.109 | 0.035 | .002 | −0.176 to −0.041 |
Chronic respiratory disease | −0.055 | 0.021 | .007 | −0.096 to −0.015 | −0.057 | 0.021 | .006 | −0.098 to −0.016 |
Arthritis | −0.084 | 0.019 | 0 | −0.121 to −0.047 | −0.083 | 0.019 | 0 | −0.120 to −0.046 |
Bone fracture/soft-tissue trauma | −0.075 | 0.016 | 0 | −0.106 to −0.043 | −0.074 | 0.016 | 0 | −0.106 to −0.042 |
Smoking history | −0.031 | 0.012 | .009 | −0.054 to −0.008 | −0.033 | 0.012 | .006 | −0.057 to −0.010 |
Thrombophilia | 0.048 | 0.019 | .014 | 0.010 to 0.086 | 0.047 | 0.020 | .016 | 0.009 to 0.086 |
Proximal VTE event | −0.048 | 0.012 | 0 | −0.072 to −0.024 | −0.048 | 0.012 | 0 | −0.072 to −0.024 |
Recurrent VTE event during follow-up | Not included | −0.008 | 0.032 | .811 | −0.070 to 0.055 | |||
Bleeding event during follow-up | Not included | −0.013 | 0.027 | .634 | −0.065 to 0.040 |
Abbreviations: BMI, body mass index; Obs.: number of observations of index scores (per patient could contribute multiple, up to 5, observations); VTE, venous thromboembolism.