Table 1.
Functional categories of 108 genes whose deletion mutants are sensitive to 0.03% SDS
Function | Genes | |||||||
---|---|---|---|---|---|---|---|---|
Metabolism (16) | PRS3* | THR4** | ARG82**** | REG1*** | IPK1*** | ARO1***** | TRP1***** | TRP5***** |
ELM1***** | AYT1* | ELO3***** | ARO7***** | ARO2**** | NRK1**** | GRR1**** | ERG3**** | |
Cell cycle and DNA processing (14) | NEM1**** | CDC50***** | SLX5*** | PHO85*** | MSH1*** | DCC1*** | EAF1** | XRS2 |
RSC2*** | FYV6**** | ARP5** | CTF4** | RSC1* | SLX8* | |||
Transcription (14) | BRE1** | BDF1***** | DEP1* | SAC3**** | MOT2***** | DEG1*** | SFL1* | POP2**** |
CTK1*** | LSM1* | SRB5*** | SPT4* | IKI3*** | SGF29* | |||
Cellular transport, transport facilities and transport routes (28) | GOS1**** | PHO87** | VPS23***** | VMA3***** | YPT31**** | LOA1*** | VMA13**** | VPS22***** |
VPS36***** | VPS38**** | VPS37***** | VPS63***** | VPS24**** | VPS25***** | RCY1***** | VPS51**** | |
CHS5***** | VPS32***** | ISA1**** | PIL1** | VMA5**** | VPS20***** | VPS16***** | VPS1***** | |
VPS33***** | VPS64** | VMA21***** | VID22**** | |||||
Protein with binding function or cofactor requirement (structural or catalytic) (9) | DIA4**** | RPL35A** | NUP84** | APL2**** | MAP 1** | RPL13B** | CBP3** | HIT1* |
OCT1** | ||||||||
Biogenesis of cellular components (5) | MDM10*** | MRPL32* | MRPL24** | GIM5* | MDM20***** | |||
Cell wall integrity and osmotic stress response (7) | TUS1*** | ROM2*** | SIT4*** | TOH1***** | SLG1* | LAS21** | PBS2**** | |
Unclassified proteins (15) | SRF1* | YDL041W* | YLR358C** | YNL296W*** | YPR123C*** | YDR149C* | YOR331C***** | YGR272C* |
YLR374C* | YKL136W* | YGR160W* | BRP1**** | BUD30* | API2** | YDR008C* |
The number of asterisks represents SDS-sensitivity of different mutants. Mutant with five asterisks was most sensitive to SDS stress, while mutant with one asterisk was least sensitive to SDS