Table I.
miRNAs reported in colorectal cancer.
| miRNAs | Expression | Target | Features | Reference |
|---|---|---|---|---|
| miR-17 | ↑ | PTEN | Invasion and migration | (11) |
| miR-18a | ↑ | ATM | DNA repair | (12) |
| miR-19a | ↑ | TIA1 | Proliferation and migration | (13) |
| miR-19b | ↑ | ITGB8 | Growth and metastasis | (14) |
| miR-20a | ↑ | GABBR1,SMAD4, SENP1, BNIP2, etc. | Proliferation, apoptosis, invasion, migration, chemo-resistance | (15–17) |
| miR-21 | ↑ | PDCD4 | Invasion, migration, intravasation, | (18) |
| miR-30a | ↓ | Metadherin | Invasion and migration | (19) |
| miR-31 | ↑ | RASA1 | Growth and proliferation | (20) |
| miR-34a | ↓ | Sirt1 and E2F3 | Chemo-resistance | (21) |
| miR-92a | ↑ | PTEN | Invasion and migration | (22) |
| miR-99a | ↓ | KRAS | Drug resistance | (23) |
| miR-128 | ↓ | SIRT1 | Apoptosis | (24) |
| miR-145 | ↓ | MAP4K4 | Migration | (25) |
| miR-149 | ↓ | FOXM1 | Invasion and migration | (26) |
| mR-198 | ↓ | ADAM28 | Proliferation | (27) |
| miR-296 | ↓ | ARRB1 | Cell growth and apoptosis | (28) |
| miR-383 | ↓ | PAX6 | Proliferation and invasion | (29) |
| miR-410 | ↑ | DKK-1 | Proliferation, migration and invasion | (30) |
| miR-452 | ↑ | GSK3β | Proliferation and migration | (31) |
| miR-598 | ↑ | INPP5E | Proliferation and cell cycle | (32) |
| miR-769 | ↓ | CDK1 | Proliferation, apoptosis, migration and invasion | (33) |
| miR 3666 | ↓ | SATB2 | Proliferation, migration and invasion | (34) |
| miR-7702 | ↓ | TADA1 | Invasion and migration | (35) |
↑, up; ↓, down; miR, microRNA.