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. 2020 Jan 15;19(3):2103–2112. doi: 10.3892/etm.2020.8453

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 8. — Apoptosis in the spinal cord following TLE. (A) Caspase-3 was not detected in the control group spinal cord tissues. Increased expression levels of caspase-3 were observed in the spinal cord after TLE in the (B) PL and (C) KA groups. Scale bar, 500 µm. (D) Quantification of the average number of casapase-3⁺ cells. (H) Multiple-staining (E) of caspase-3, (F) albumin ad the (G) nucleus indicated a small degree of caspase-3 staining in albumin⁺ cells. Arrow one, merged caspase-3 and nuclei staining. Arrow two, merged caspase-3, albumin and nuclei staining. TLE, temporal lobe epilepsy; PL, pilocarpine; KA, kainic acid.