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. 2020 Jan 14;19(3):2059–2066. doi: 10.3892/etm.2020.8449

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — miR-584 promotes drug sensitivity to cisplatin in cervical cancer cells. HeLa and CaSki cells transfected with miR-584 mimics or miR-NC were incubated with or without 10 µM cisplatin for 24 h. Overexpression of miR-584 increased the proportion of apoptotic cells compared with the miR-NC group in HeLa and CaSki cells. The combination of miR-584 and cisplatin significantly enhanced the apoptosis rate of HeLa and CaSki cells compared with cisplatin or miR-584 mimics, respectively. (A) The apoptosis rate of HeLa. (B) The apoptosis rate of CaSki. *P<0.05. miR, microRNA; miR-NC, mimic negative control.