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. 2020 Jan 23;19(3):2229–2235. doi: 10.3892/etm.2020.8470

Figure 2.

Figure 2.

miR-489 overexpression inhibited the viability and differentiation of CFs. (A) miR-489 expression, and (B) Col1A1 and α-SMA mRNA levels in CFs transfected with NC and miR-489 mimic were determined by reverse transcription-quantitative polymerase chain reaction. *P<0.05 vs. NC group. (C) An MTT assay was used to investigate the viability of CFs transfected with NC and miR-489 mimic treated with ISO. The data are presented as the mean ± standard deviation. *P<0.05 and **P<0.01. miR, microRNA; CFs, cardiac fibroblasts; NC, negative control; Col1A1, collagen I; α-SMA, α-smooth muscle actin.