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. 2020 Feb 11;11:44. doi: 10.3389/fphar.2020.00044

Table 1.

Baseline characteristics before and after propensity-score matching.

Characteristic Amlodipine group (n = 868) Control group (n = 1,798) Matched control group (n = 868) P1 P2
Age
Mean (years) 63.66±9.51 63.46±9.45 63.79±9.92 0.613 0.778
Distribution
<60 years 203 (23.39%) 696 (38.54%) 242 (27.88%)
≥60 years 665 (76.61%) 1,102 (61.29%) 626 (72.12%) <0.001 0.032
Sex (%)
Male 537 (61.87%) 1,110 (61.74%) 542 (62.44%) 0.032 0.850
Female 331 (38.13%) 688 (38.26%) 326 (37.56%)
Body mass index, kg/m2 24.62±3.45 24.36±3.28 24.34±3.31 0.062 0.094
Scr 94.50±47.75 90.27±47.75 95.50±52.71 0.032 0.693
GFR 82.18±38.48 84.25±38.48 80.48±32.08 0.194 0.377
Contrast type
Low-osmolar 673 (77.53%) 1,474 (82.39%) 708 (81.57%) 0.007 0.037
Iso-osmolar 151 (17.40%) 298 (16.66%) 152 (17.51%) 0.595 0.950
High-osmolar 1 (0.12%) 26 (1.45%) 8 (0.92%) 0.001 0.019
Diabetes 296 (34.10%) 501 (27.86%) 285 (32.83%) 0.001 0.576
Anemia 352 (40.55%) 823(45.77%) 436 (50.23%) 0.011 <0.001
Hyperlipidemia 92 (10.60%) 136 (7.56%) 73 (8.41%) 0.010 0.088
Killip III 94 (10.83%) 152 (8.45%) 76 (8.76%) 0.109 0.146
Medications
Diuretic 159 (18.32%) 372 (20.69%) 188 (21.66%) 0.196 0.082
ACEI 417 (48.04%) 776 (43.16%) 380 (43.78%) 0.553 0.068
ARB 174 (20.04%) 227 (12.63%) 104 (11.98%) <0.001 <0.001
β-blockers 473 (54.49%) 848 (47.16%) 414 (47.70%) <0.001 0.005
Aspirin 552 (63.59%) 957 (53.23%) 465 (53.57%) 0.003 <0.001
Alprostadil 193 (22.24%) 351 (19.52%) 166 (19.12%) 0.087 0.123

eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; CKD, chronic kidney disease [defined as eGFR <60 mL/(min 1.73 m2)]; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; CI-AKI, contrast-induced acute kidney injury; P1, Amlodipine group vs Control group; P2, Amlodipine group vs Matched control group.