Table 3.
The association between amlodipine and CI-AKI in the subgroups.
| Outcome | Amlodipine group | Control group | Matched control group | P1 | P2 |
|---|---|---|---|---|---|
| No. of Diabetes | 296 | 500 | 285 | ||
| CI-AKI | 25 (8.45%) | 67 (13.40%) | 41 (12.89%) | ||
| OR | 0.598 (0.368–0.969) | 0.549 (0.324–0.930) | 0.035 | 0.024 | |
| No. of CKD | 205 | 382 | 200 | ||
| CI-AKI | 16 (7.80%) | 45 (11.78%) | 30 (13.79%) | ||
| OR | 0.634 (0.349–1.152) | 0.480 (0.253–0.911) | 0.132 | 0.023 | |
| No. of non-CKD | 663 | 1,416 | 668 | ||
| CI-AKI | 53 (7.99%) | 166 (11.72%) | 83 (12.43%) | ||
| OR | 0.654 (0.473–0.905) | 0.612 (0.426–0.880) | 0.01 | 0.008 | |
| No. of elderly | 665 (7.52%) | 1,331 (12.47%) | 635 (14.33%) | ||
| CI-AKI | 50 | 166 | 91 | ||
| OR | 0.571 (0.410–0.794) | 0.486 (0.338–0.699) | <0.001 | <0.001 | |
| No. of low-osmolar | 673 | 1,474 | 708 | ||
| CI-AKI | 55 (8.17%) | 177 (12.01%) | 98 (13.84%) | ||
| OR | 0.652 (0.475–0.896) | 0.554 (0.391–0.785) | 0.008 | 0.001 | |
| No. of iso-osmolar | 151 | 298 | 152 | ||
| CI-AKI | 10 (6.62%) | 32 (10.74%) | 15 (9.87%) | ||
| OR | 0.590 (0.282–1.234) | 0.648 (0.281–1.491) | 0.157 | 0.305 |
CI-AKI, contrast-induced acute kidney injury; P1, Amlodipine group vs Control group; P2, Amlodipine group vs Matched control group.