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. Author manuscript; available in PMC: 2020 Feb 18.
Published in final edited form as: Cell Physiol Biochem. 2019;53(2):400–412. doi: 10.33594/000000146

Fig. 3.

Fig. 3.

Aggresomal degradation pathway. HEK-293 cell lines stably expressing (A) A1038V, or (B) G1961E were treated for 16 h with increasing doses of the aggresome inhibitor tubacin. Data are normalized to the 0 μM control. *P<0.05. n=3–4. Ezrin was used as the loading control. The A1038 V and G1961E mutants are significantly degraded in the aggresome.