Comparison 1. Hormone replacement therapy versus no hormone replacement therapy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Overall survival	3	350	Hazard Ratio (95% CI)	0.71 [0.54, 0.93]
2 Quality of life, general condition	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
3 Progression‐free survival	2	275	Hazard Ratio (95% CI)	0.76 [0.57, 1.01]
4 Incidence of breast cancer	2	225	Risk Ratio (M‐H, Fixed, 95% CI)	2.0 [0.19, 21.59]
5 Transient ischaemic attack	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
6 Cerebrovascular accident	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
7 Myocardial infarction	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected