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. 2020 Jan 24;68(2):e12630. doi: 10.1111/jpi.12630

Figure 6.

Figure 6

Comparison of the binding mode of melatonin with JV5 and JV8. A, The binding mode of melatonin (brown; PDB code 6TR5) is overlaid with indazole 38, JV5 (green sticks, PDB code 6R8Q) and B, with isoquinoline 45, JV8 (grey sticks, PDB code 6R8R). The main chain of Notum is shown as Cα trace and side chains of residues W128 and A342 as sticks