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. Author manuscript; available in PMC: 2020 Feb 20.
Published in final edited form as: Stat Med. 2019 Dec 4;39(4):438–455. doi: 10.1002/sim.8415

TABLE 5.

Simulation scenarios and nominal size, along with the empirical type I error rates corresponding to the MAQLS z-test and t-test (DoF = I − 2) with different variance estimators. Empirical type I error rates between 4.5% and 5.5% are highlighted in boldface and considered acceptable based on the margin of error from a binomial model with 10 000 Monte Carlo replications. Pred: nominal type I error rate; MB: model-based variance; BC0: uncorrected sandwich variance of Liang and Zeger (1986); BC1: bias-corrected sandwich variance of Kauermann and Carroll (2001); BC2: bias-corrected sandwich variance of Mancl and DeRouen (2001); BC3: bias-corrected sandwich variance of Fay and Graubard (2001)

z-test t-test
τ ρ δ I N T Pred MB BC0 BC1 BC2 BC3 Pred MB BC1 BC2 BC2 BC3
0.03 0.2 0 18 10 7 5.0 4.8 8.4 6.8 5.1 7.1 5.0 3.4 6.3 4.7 3.8 4.9
0.03 0.2 0 18 24 4 5.0 4.9 8.1 6.5 5.0 6.5 5.0 3.4 6.0 4.7 3.6 4.7
0.03 0.2 0 20 14 5 5.0 5.1 8.3 6.9 5.8 7.0 5.0 3.8 6.5 5.4 4.4 5.5
0.03 0.2 0 21 8 4 5.0 5.2 7.9 6.6 5.3 6.6 5.0 3.8 6.2 5.0 4.0 4.9
0.03 0.2 0 15 8 4 5.0 5.7 9.7 7.7 5.8 7.7 5.0 3.7 7.0 5.3 4.1 5.3
0.03 0.8 0 16 12 5 5.0 5.6 9.0 7.3 5.6 7.3 5.0 3.8 6.7 5.1 3.8 5.1
0.03 0.8 0 24 7 5 5.0 5.3 7.7 6.6 5.5 6.6 5.0 4.3 6.2 5.2 4.3 5.3
0.03 0.8 0 12 8 5 5.0 6.0 10.6 7.9 5.8 7.9 5.0 3.5 7.0 4.9 3.2 5.0
0.03 0.8 0 12 5 4 5.0 5.7 10.3 7.8 5.7 7.5 5.0 3.4 6.9 5.0 3.5 4.9
0.03 0.8 0 10 5 3 5.0 6.3 11.2 8.2 5.6 7.1 5.0 3.0 7.0 4.6 3.1 3.8
0.10 0.2 0 21 11 8 5.0 5.0 8.1 6.9 5.7 7.0 5.0 3.8 6.6 5.3 4.4 5.6
0.10 0.2 0 24 11 7 5.0 5.1 7.7 6.4 5.3 6.5 5.0 3.8 6.1 5.1 4.3 5.2
0.10 0.2 0 15 16 6 5.0 4.8 9.7 7.5 5.7 7.8 5.0 3.1 6.8 5.2 4.0 5.3
0.10 0.2 0 18 8 7 5.0 4.8 8.8 7.1 5.6 7.3 5.0 3.4 6.7 5.2 4.0 5.4
0.10 0.2 0 16 7 5 5.0 5.2 9.1 7.2 5.5 7.3 5.0 3.4 6.6 5.1 3.8 5.2
0.10 0.8 0 20 18 5 5.0 5.3 7.9 6.4 5.2 6.5 5.0 3.8 6.1 4.8 3.9 4.8
0.10 0.8 0 15 9 4 5.0 5.5 9.1 7.2 5.3 7.0 5.0 3.7 6.6 4.8 3.7 4.6
0.10 0.8 0 10 20 3 5.0 5.6 11.7 8.5 6.0 7.4 5.0 2.8 7.3 4.9 3.0 4.0
0.10 0.8 0 12 5 5 5.0 5.8 10.5 7.9 5.7 7.9 5.0 3.3 6.9 4.9 3.3 4.9
0.10 0.8 0 9 7 4 5.0 6.0 12.0 8.6 5.7 8.3 5.0 2.8 7.2 4.7 2.9 4.5