Schuh 1992.

Methods	Randomised double blind controlled trial. Parallel group study.
Participants	69 infants (49 male, 20 females), aged 6 weeks to 24 months. First episode of wheeze presenting to an emergency department. Excl. cyanosis, resp rate > 90/min prsentation between 24.00 and 08.00am., previous wheeze, mechanical ventilation after birth. recurrent aspiratiopn, concurrent cardiopulmonarty disease, previous bronchodilator therapy
Interventions	1) Albuterol 0.15mg/kg + ipratropium bromide 250 mcg 2) Albuterol 0.15mg/kg + 0.9% saline placebo Administered via jet nebulised 1 hour apart.
Outcomes	Decline in respiratory rate from baseline at 120 minutes.
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ Adequate