Table 3.
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Paroxysmal AF (n = 387) | ||||
Age, y | 0.989 (0.959‐1.021) | .499 | 0.970 (0.935‐1.008) | .117 |
Male sex | 0.470 (0.233‐0.948) | .035* | 0.537 (0.172‐1.677) | .284 |
BSA, m2 | 0.131 (0.019‐0.913) | .040* | 0.402 (0.015‐10.490) | .584 |
BMI, kg/m2 | 0.940 (0.836‐1.056) | .295 | ||
Heart failure | 0.722 (0.211‐2.475) | .605 | ||
Hypertension | 1.294 (0.646‐2.593) | .467 | ||
Diabetes mellitus | 0.696 (0.236‐2.057) | .513 | ||
Stroke or TIA | 2.106 (0.929‐4.775) | .075 | ||
Vascular disease | 1.298 (0.510‐3.300) | .584 | ||
LA diameter, mm | 0.958 (0.899‐1.021) | .187 | ||
LAVI, mL/m2 | 1.003 (0.975‐1.032) | .820 | ||
LV ejection fraction (%) | 1.014 (0.970‐1.060) | .544 | ||
E/Em | 0.939 (0.845‐1.043) | .238 | ||
LA voltage, mV | 0.386 (0.173‐0.862) | .020* | 0.455 (0.191‐1.086) | .076 |
AF duration, y | 0.923 (0.815‐1.046) | .208 | 0.983 (0.870‐1.110) | .781 |
Persistent AF (n = 618) | ||||
Age, y | 0.996 (0.981‐1.011) | .588 | 0.990 (0.971‐1.010) | .336 |
Male sex | 1.063 (0.721‐1.569) | .757 | 1.047 (0.626‐1.752) | .860 |
BSA, m2 | 1.364 (0.569‐3.267) | .486 | ||
BMI, kg/m2 | 1.008 (0.961‐1.058) | .737 | ||
Heart failure | 0.519 (0.325‐0.829) | .006* | 0.429 (0.230‐0.800) | .008* |
Hypertension | 1.029 (0.744‐1.423) | .863 | ||
Diabetes mellitus | 0.729 (0.469‐1.133) | .160 | ||
Stroke or TIA | 0.788 (0.497‐1.250) | .312 | ||
Vascular disease | 1.034 (0.658‐1.625) | .886 | ||
LA diameter, mm | 1.042 (1.012‐1.073) | .005* | 1.058 (1.015‐1.102) | .007* |
LAVI, mL/m2 | 1.008 (0.995‐1.021) | .234 | ||
LV ejection fraction (%) | 1.009 (0.991‐1.029) | .322 | ||
E/Em | 0.976 (0.939‐1.014) | .207 | ||
LA voltage, mV | 0.331 (0.213‐0.514) | <.001* | 0.365 (0.227‐0.586) | <.001* |
AF duration, y | 1.065 (1.033‐1.099) | <.001* | 1.064 (1.025‐1.104) | .001* |
Abbreviations: AF, atrial fibrillation; BMI, body mass index; BSA, body surface area; CI, confidence interval; E/Em, early mitral inflow velocity over the early diastolic mitral annular velocity; HR, hazard ratio; LA, left atrium; LAVI, left atrial volume index; LV, left ventricle; TIA, transient ischemic attack.
P < .05.