Table 1.
Number of families | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Family members of probands | Number of cancer cases among family members | Familial cancers | ||||||||||
Primary site | ICD‐10 | Number | Person‐years | 01 | 1 | 2 | 3 | 4 | >4 | Total1 | Number of cancers | Number of families (proportion of families with familial cancers) |
Brain and other CNS | C70–72, D32–33, D42–43 | 49,712 | 935,387 | 5,346 | 76 | 0 | 1 | 0 | 12 | 5,424 | 85 | 78 (1.4) |
Colorectum | C18–20 | 20,536 | 383,189 | 1,922 | 33 | 5 | 1 | 0 | 0 | 1,961 | 46 | 39 (2.0) |
Breast | C50 | 54,766 | 992,156 | 5,465 | 96 | 2 | 0 | 0 | 0 | 5,563 | 100 | 98 (1.8) |
Melanoma | C43 | 29,894 | 536,409 | 3,070 | 26 | 0 | 0 | 0 | 0 | 3,096 | 26 | 26 (0.8) |
Other primary | C00–17, C21–42, C44–49, C51–69, C73–96 D09.0‐1, D41, D45–47, D76 | 226,870 | 2,650,641 | 24,231 | 253 | 8 | 1 | 1 | 0 | 24,494 | 276 | 263 (1.1) |
Total | 376,7623 | 40,034 | 484 | 15 | 3 | 1 | 1 | 40,538 |
Excludes families where proband has no family members.
Six cancers in one family.
The number of unique relatives.