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. 2019 Jun 27;146(7):1791–1799. doi: 10.1002/ijc.32512

Table 1.

Numbers of family members of probands and their person‐years, number of families by number of cancer cases among family members and number of familial cancers and of families with familial cancers by primary site, including follow‐up and cancer cases of family members at 0–40 years of age

Number of families
Family members of probands Number of cancer cases among family members Familial cancers
Primary site ICD‐10 Number Person‐years 01 1 2 3 4 >4 Total1 Number of cancers Number of families (proportion of families with familial cancers)
Brain and other CNS C70–72, D32–33, D42–43 49,712 935,387 5,346 76 0 1 0 12 5,424 85 78 (1.4)
Colorectum C18–20 20,536 383,189 1,922 33 5 1 0 0 1,961 46 39 (2.0)
Breast C50 54,766 992,156 5,465 96 2 0 0 0 5,563 100 98 (1.8)
Melanoma C43 29,894 536,409 3,070 26 0 0 0 0 3,096 26 26 (0.8)
Other primary C00–17, C21–42, C44–49, C51–69, C73–96 D09.0‐1, D41, D45–47, D76 226,870 2,650,641 24,231 253 8 1 1 0 24,494 276 263 (1.1)
Total 376,7623 40,034 484 15 3 1 1 40,538
1

Excludes families where proband has no family members.

2

Six cancers in one family.

3

The number of unique relatives.