Table 1.
Numbers of family members of probands and their person‐years, number of families by number of cancer cases among family members and number of familial cancers and of families with familial cancers by primary site, including follow‐up and cancer cases of family members at 0–40 years of age
Number of families | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Family members of probands | Number of cancer cases among family members | Familial cancers | ||||||||||
Primary site | ICD‐10 | Number | Person‐years | 01 | 1 | 2 | 3 | 4 | >4 | Total1 | Number of cancers | Number of families (proportion of families with familial cancers) |
Brain and other CNS | C70–72, D32–33, D42–43 | 49,712 | 935,387 | 5,346 | 76 | 0 | 1 | 0 | 12 | 5,424 | 85 | 78 (1.4) |
Colorectum | C18–20 | 20,536 | 383,189 | 1,922 | 33 | 5 | 1 | 0 | 0 | 1,961 | 46 | 39 (2.0) |
Breast | C50 | 54,766 | 992,156 | 5,465 | 96 | 2 | 0 | 0 | 0 | 5,563 | 100 | 98 (1.8) |
Melanoma | C43 | 29,894 | 536,409 | 3,070 | 26 | 0 | 0 | 0 | 0 | 3,096 | 26 | 26 (0.8) |
Other primary | C00–17, C21–42, C44–49, C51–69, C73–96 D09.0‐1, D41, D45–47, D76 | 226,870 | 2,650,641 | 24,231 | 253 | 8 | 1 | 1 | 0 | 24,494 | 276 | 263 (1.1) |
Total | 376,7623 | 40,034 | 484 | 15 | 3 | 1 | 1 | 40,538 |
Excludes families where proband has no family members.
Six cancers in one family.
The number of unique relatives.