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. 2019 Dec 9;126(5):1031–1040. doi: 10.1002/cncr.32590

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© 2019 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/3.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Cubic spline curves for specific cancer risks against continuous total amount of lifetime alcohol consumption. ORs (solid line) and 95% CIs (dashed line) were estimated by conditional logistic regression, mutually adjusted for smoking history, occupational class, and comorbidities. The numbers of subjects used for the analyses were as follows: (A) 2090 (Lip, oral cavity, and pharynx), (B) 2,816 (Esophagus), (C) 18,710 (Stomach), (D) 19,274 (Colon and rectum), (E) 7208 (Liver), (F) 2700 (Gallbladder and bile duct), (G) 2992 (Pancreas), (H) 1098 (Larynx), (I) 11,944 (Lung), (J) 442 (Bone and soft tissue), (K) 2070 (Skin), (L) 8904 (Breast), (M) 1292 (Cervix uteri), (N) 1650 (Corpus uteri), (O) 1044 (Ovary), (P) 16,742 (Prostate), (Q) 2356 (Kidney), (R) 1332 (Renal pelvis and ureter), (S) 6584 (Bladder), (T) 766 (Brain and nerve system), (U) 1312 (Thyroid), (V) 4354 (Malignant lymphoma), (W) 938 (Multiple myeloma), and (X) 1232 (Leukemia).