4A: Unadjusted temporal trends of in-hospital mortality in acute myocardial infarction-cardiogenic shock; all p<0.001 for trend; 4B: Adjusted multivariate logistic regression for in-hospital mortality temporal trends in acute myocardial infarction-cardiogenic shock with 2000 as referent year; adjusted for age, sex, race, primary payer, socio-economic status, hospital location/teaching status, hospital bedsize, comorbidity, acute organ failure, cardiac arrest, coronary angiography, percutaneous coronary intervention, invasive hemodynamic monitoring, mechanical circulatory support, invasive mechanical ventilation, hemodialysis; all p<0.001 for trend