Table 1:

Drugs that cause synthetic lethality in IDH1 mutated neoplasms

Type	Compound Name	Target	References
Drugs	GMX1778, FK866	NAMPT	[29]
	Temozolomide	DNA-damage	[30]
	CB-839	Glutaminase inhibitor	[31]
	PARP inhibitors	PARP	[32], [54]
	ABT199	Bcl-2	[19]
	ABT263	Bcl-xL (Bcl-2)	[38]
Radiation		DNA-damage	[26]