Table 4.

Logistic Regression Models with Early and Late Variables^a

Characteristic	Odds ratio (95% CI)	P-value
Survival to 12 monthsb
Acquired heart disease		0.014
No	Reference
Yes	0.30 (0.11, 0.78)
Gastrointestinal condition		0.031
No	Reference
Yes	0.38 (0.15, 0.92)
Minimum Lactate (mmol/L)c	0.64 (0.49, 0.84)	0.001
Survival to 12 months with VABS-II decreased ≤ 15 points from baselined,e
Gastrointestinal condition		0.022
No	Reference
Yes	0.21 (0.06, 0.80)
Minimum Lactate (mmol/L)c	0.68 (0.48, 0.97)	0.035
Open-chest cardiac massage		0.036
No	Reference
Yes	2.57 (1.06, 6.22)
Treatment Assigned		0.053
Hypothermia	0.41 (0.17, 1.01)
Normothermia	Reference
Survival to 12 months with VABS-II ≥ 70d,f
Gastrointestinal condition		0.006
No	Reference
Yes	0.17 (0.05, 0.60)
Minimum Lactate (mmol/L)c	0.78 (0.61, 0.99)	0.038

^aModels include variables available through THAPCA day 2. Day of randomization is day 0.

^bModeling is based on the 139 complete records in which all potential predictors and the outcome are non-missing.

^cTime interval is from 2 hours before to 48 hours after the start of the temperature management intervention.

^dVABS-II is Vineland Adaptive Behavior Scales, Second Edition.

^eModeling is based on the 142 complete records in which all potential predictors and the outcome are non-missing.

^fModeling is based on the 122 complete records in which all potential predictors and the outcome are non-missing.