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. Author manuscript; available in PMC: 2020 Feb 18.
Published in final edited form as: Chem Res Toxicol. 2018 Dec 19;32(1):80–89. doi: 10.1021/acs.chemrestox.8b00202

Figure 3.

Figure 3.

Ion-current profiles of the mass transitions of AFB1-N7-Gua, cis-AFB1-FapyGua, and trans-AFB1-FapyGua and their 15N5-labeled analogues recorded during the LC-MS/MS analysis of a liver DNA sample from a control mouse (A) and an AFB1-treated mouse (B). For each of the three adducts, two mass transitions shown in Figure 2 were used. The arrows in (A) show the elution positions of AFB1-N7-Gua, cis-AFB1-FapyGua, and trans-AFB1-FapyGua and indicate their absence in liver DNA of control mice.