4. Symptomatic UTIs.
| Study name | Pre cross‐over | P value | End of study data | P value | Notes |
| Schlager 1999 | NS | NS | Cranberry: 3 UTIs in 2 children Placebo: 3 UTIs in 3 children |
NS | |
| Avorn 1994 | N/A | N/A | Cranberry: 20/473 (4%) Placebo: 37/498 (7%) |
Not significant (P value NS) | Denominator unclear |
| Walker 1997 | NS | NS | Cranberry: 6 UTIs Placebo: 15 UTIs |
P < 0.05 | Whilst taking cranberry capsules as opposed to placebo, 7/10 subjects exhibited fewer UTIs, 2 subjects exhibited the same number of UTIs, and 1 subject experienced 1 more UTI. |
| Foda 1995 | NS | NS | Cranberry: 19/112 months (17%) Placebo: 20/117 months (17.1%) |
NS | Months with positive/significant culture and UTI symptoms |
| Haverkorn 1994 | NS | No details provided | |||
| Lee 2007 | N/A | N/A | Cranberry: 67/153 Cranberry placebo: 71/152 Methenamine hippurate: 67/150 Methenamine hippurate placebo: 71/55 |
Hazard ratio cranberry 0.93 (95% CI 0.66‐1.29) | |
| Wing 2008 | N/A | N/A | Cranberry 1 dose: 2/67 Cranberry 2‐3 doses: 2/58 Placebo: 0/63 |
NS | This study reported symptomatic UTI and positive culture results, these results are symptomatic UTI |
| Hess 2008 | Pre‐trial: 1.3 UTIs/ person/y | NS | During the cranberry period, 6 participants had 7 UTI, compared with 16 subjects and 21 UTI in the placebo period. The frequency of UTI was reduced to 0.3 UTI/y vs 1.0 UTI/y while receiving placebo. |
P < 0.05 | This study reported symptomatic UTI and positive culture results, these results are symptomatic UTI |
| Ferrara 2009 | N/A | N/A | Cranberry: 5/27 Lactobacillus: 11/26 No treatment: 18/27 |
P < 0.5 cranberry vs Lactobacillus groups and control | |
| McMurdo 2009 | N/A | N/A | Cranberry: 25/69 Antibiotic: 14/68 |
P = 0.084 | Only 19/39 symptomatic UTIs had positive culture results |
| Salo 2010 | N/A | N/A | Cranberry: 20/125 Placebo: 28/127 |
P = 0.21 | This data are during 12 months but participants were only treated for 6 months. On‐treatment data are not reported |
| Barbosa‐Cesnik 2011 | N/A | N/A | Cranberry: 31/155 Placebo: 23/164 |
P = 0.21 | |
| NAPRUTI Study 2011 I | N/A | N/A | Cranberry: 78.2% Antibiotic: 71.1% |
P = 0.03 | These UTI results are for clinical UTI not necessarily microbiologically determined |
| Sengupta 2011 | N/A | N/A | Cranberry (500 mg/d): 2/21 Cranberry (1000 mg/d): 2/23 No treatment: 4/12 |
NS | |
| Cowan 2012 | N/A | N/A | Cranberry: 26/59 Placebo: 23/59 |
P = 0.28 | This data are symptomatic UTI not necessarily culture proven |
N/A ‐ not applicable; NS ‐ not stated