PACS Study 2008.

Methods	Study design: 3‐arm parallel RCT Power calculation: no Intention‐to‐treat analysis: appears all were included
Participants	Setting: 4 dementia units Country: USA Elderly mean and women > 60 years of age with dementia and a resident of a nursing home or assisted living facility for > 30 days Number: 56 randomised and analysed
Interventions	Treatment group 1 Cranberry capsule: 1 x 650 mg once daily Treatment group 2 Cranberry capsule: 1 x 650 mg twice daily Control group No treatment
Outcomes	Number of urine cultures collected Number of participants with E.coli isolated from urine culture Number of participants with > 100,000 cfu/mL if any organism
Notes	Details from clinical trials register, not from a published paper Designed as a feasibility pilot for a larger study, wanted to determine if collecting urine was feasible
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No details on this aspect
Allocation concealment (selection bias)	Unclear risk	Open label study, could be possible to subvert randomisation
Blinding of participants and personnel (performance bias) All outcomes	High risk	Open label study
Blinding of outcome assessment (detection bias) All outcomes	High risk	Open label
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Expected number of urine samples was less than expected. Losses to follow‐up/withdrawals: 2 lost and 28 did not complete treatment
Selective reporting (reporting bias)	Unclear risk	Outcomes are about feasibility not efficacy
Other bias	Unclear risk	Many details missing or poorly detailed Source of funding: NS