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| Methods | Multi‐centre, parallel‐group study | |
| Participants | 220 patients aged 18‐70 | |
| Interventions | Tizanidine (2‐36mg) v. placebo | |
| Outcomes | Primary end‐points: Ashworth score, patient diaries (muscle spasm & clonus scores). Secondary end‐points: reflexes, clonus, spasms (assessed by physician), muscle power (MRC grade), walking time, ADL, global evaluation of efficacy | |
| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Unclear risk | B ‐ Unclear |
