Wade 2003.
Methods | Crossover study with 2 week blocks, without intervening washout periods | |
Participants | 24 patients with intractable neurogenic symptoms, 18 with MS | |
Interventions | THC v. CBD v. 1:1 mixture of THC:CBD v. placebo | |
Outcomes | daily patient visual analogue scales, Ashworth score, numerical investigator rating of symptoms | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | High risk | C ‐ Inadequate |