| Methods |
Randomised controlled trial |
| Participants |
150 patients undergoing major abdominal surgery |
| Interventions |
1) 6% HES, LMW (n = 50)
2) 6% HES, MMW (n = 50)
3) 3% MFG (n = 50)
To keep MAP > 70 mmHg and CVP between 10 mmHg and 14 mmHg
Volume was given perioperatively until the morning of the first postoperative day. For each hour of surgery 500 mL to 800 mL of crystalloids was routinely infused |
| Outcomes |
Death
Haemodynamic variables
Blood loss
Blood transfused
Cost |
| Notes |
Follow‐up 1 postoperative day. Deaths recorded after study period. Information on allocation concealment was obtained on contact with the study authors |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Low risk |
Adequate. Sequentially numbered sealed opaque envelopes |
