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. 2012 Jul 11;2012(7):CD001319. doi: 10.1002/14651858.CD001319.pub5

Gondos 2010.

Methods Randomised controlled study
Participants 200 postoperative haemodynamically stable hypovolaemic patients needing intensive care treatment because of general health status. Exclusion criteria: aged < 18 years, active bleeding or shock, severe pulmonary oedema, known uraemia, anaphylactic reaction to colloid fluids, and life expectancy less than 24 hours
Interventions 1) 4% Gelatin (n = 50)
2) 6% HES (n = 50)
2) 5% HA (n = 50)
A fourth group were given LR (n = 50)
Outcomes Death
Haemodynamic variables
Length of ICU stay
Notes Final follow‐up 10th postoperative day. Additional information on allocation obtained from study author
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Low risk Adequate ‐ 'randomised by blinded envelope technique ‐ each centre had got 20 closed, opaque envelopes which were sequentially numbered'