| Methods |
Randomised controlled trial. Surgeons blinded to the fluid administered although the anaesthetist was aware of the fluid administered to a given patient |
| Participants |
40 adults scheduled to undergo radical retropubic prostatomy
Exclusion criteria: coagulation disorder, platelet count < 100,000/mm3, preoperative Hb < 12 g/dL, if anticoagulant therapy within 10 days of the surgery, aspirin or NSAID use < 10 days before surgery or if they had documented allergy to any of the IV fluids used in the protocol |
| Interventions |
1) 5% HA (n = 10)
2) 6% Dextran 70 (n = 10)
3) 6% HES (n = 10)
A fourth group received RL
Haemodilution was done with the target of 9 g/dL
All patients underwent moderate haemodilution to a target of Hb 9 g/dL |
| Outcomes |
Haemodynamic variables
Blood loss and units transfused |
| Notes |
Follow‐up 3 days |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
Unclear. No information given on allocation concealment |
