| Methods |
Randomised controlled trial
Blinding unclear |
| Participants |
30 hypovolaemic patients with ITBVI < 850 in septic shock with ALI
Exclusion criteria: CVS failure (NYHA class IV), chronic respiratory failure (chronic hypoxia, hypercapnia) requiring renal replacement therapy, chronic liver failure or those with diabetes mellitus or with known aortic aneurysm |
| Interventions |
1) 6% HES (n = 15)
2) 4% GEL (n = 15)
250 mL/15‐minute boluses (max 1000 mL) were given until the end point ITBVI > 900 mL/m2
|
| Outcomes |
Death
Haemodynamic variables |
| Notes |
Follow‐up 60 minutes after the end point was reached. Follow‐up for deaths was not clear |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
Unclear |
