Schramko 2010.
Methods | Randomised controlled trial | |
Participants | 45 patients undergoing elective cardiac surgery. Exclusion criteria: known coagulation disorder; renal or hepatic failure; preoperative left ventricular ejection fraction < 40%; received warfarin, heparin, clopidogrel, or acetylsalicylic acid within previous 5 days | |
Interventions | 1) 6% HES (n = 15) 2) 4% Gelatin (n = 15) 3) Ringer's acetate (n = 15) |
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Outcomes | Haemodynamic variables Units of RBC and FFP transfused |
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Notes | Follow‐up 18 hours postoperatively. Mortality data obtained from study author (relates to study period only, inhospital mortality not available | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Low risk | Adequate 'closed envelopes were prepared before the beginning of the study by a person who did not take part in the treatment of the study subjects' |