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. 2012 Jul 11;2012(7):CD001319. doi: 10.1002/14651858.CD001319.pub5

Stockwell 1992.

Methods Randomised controlled trial. No information given on method of randomisation 
 No loss to follow‐up 
 Blinding not mentioned
Participants 475 patients admitted to the ICU. Patients were excluded from the study if they were < 18 years or if admitted for cardiac monitoring or cardiac thrombolytic therapy
Interventions 1) 4.5% Albumin (n = 226) 
 2) Synthetic colloid polygeline (Haemaccel) (n = 249) 
 for IV volume replacement
Outcomes Death 
 Length of stay in ICU 
 Incidence of renal failure 
 Pulmonary oedema
Notes Follow‐up until discharge from ICU
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk Unclear. No information given on allocation