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. 2012 Jul 11;2012(7):CD001319. doi: 10.1002/14651858.CD001319.pub5

Veneman 2004.

Methods Randomised controlled trial
Participants 61 critically ill hypoalbuminic patients (serum concentration < 20 g/L)
Interventions 1) Albumin (n = 15) 
 2) HES 10% 500 mL (n = 15) 
 3) HES 10% 1000 mL (n = 15) 
 A fourth group received saline
Outcomes Death 
 Haemodynamic variables 
 Adverse events (from study author)
Notes Follow‐up 72 hours postoperatively, mortality 30 days
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Low risk Adequate. Allocation by sealed envelopes kept outside of hospital