Yang 2011.
Methods | Randomised controlled trial. Computer‐generated random numbers | |
Participants | 90 patients aged 18 to 75 years with hepatocellular carcinoma scheduled for hepatectomy ‐ received fluids postoperatively. Exclusion criteria: renal insufficiency requiring dialysis, cardiac insufficiency, steroid therapy, pre‐existing signs of bacteraemia, and known allergic reactions to starch preparations | |
Interventions | 1) 20% HA (n = 30) 2) 6% HES (n = 30) 3) LR (n = 30) |
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Outcomes | Death Haemodynamic variables Liver function Inflammatory response parameters |
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Notes | Follow‐up until hospital discharge | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Unclear risk | Unclear |
AAA: abdominal aortic aneurysm; ALI: acute lung injury; aPPT: activated partial thromboplastin time; ASA: American Society of Anesthesiologists; COP: colloid osmotic pressure; CRF: chronic renal failure; CVP: central venous pressure; CVS: cardiovascular system; EVLW: extravascular lung water; FFP: fresh frozen plasma; HA: human albumin; Hb: haemoglobin; HES: hydroxyethyl starch; HMW: high molecular weight; ICU: intensive care unit; ITBVI: intrathoracic blood volume index; ITT: intention to treat; IV: intravenous; LMW: low molecular weight; LVEDP: left ventricular end diastolic pressure; MMW: medium molecular weight; MAP: mean arterial pressure; MFG: modified fluid gelatin; MI: myocardial infarction; NSAID: non‐steroidal anti‐inflammatory drug; NYHA: New York Heart Association; PAWP: pulmonary artery wedge pressure; PAOP: pulmonary artery occlusion pressure; PCWP: pulmonary capillary wedge pressure; PPF: plasma protein fraction; PRBC: packed red blood cell; PT: prothrombin time; RBC: red blood cell; RL: Ringer's lactate; SBP: systolic blood pressure; WP: wedge pressure.