Skip to main content
. 2012 Jul 11;2012(7):CD001319. doi: 10.1002/14651858.CD001319.pub5

Yang 2011.

Methods Randomised controlled trial. Computer‐generated random numbers
Participants 90 patients aged 18 to 75 years with hepatocellular carcinoma scheduled for hepatectomy ‐ received fluids postoperatively. Exclusion criteria: renal insufficiency requiring dialysis, cardiac insufficiency, steroid therapy, pre‐existing signs of bacteraemia, and known allergic reactions to starch preparations
Interventions 1) 20% HA (n = 30)
2) 6% HES (n = 30)
3) LR (n = 30)
Outcomes Death
Haemodynamic variables
Liver function
Inflammatory response parameters
Notes Follow‐up until hospital discharge
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk Unclear

AAA: abdominal aortic aneurysm; ALI: acute lung injury; aPPT: activated partial thromboplastin time; ASA: American Society of Anesthesiologists; COP: colloid osmotic pressure; CRF: chronic renal failure; CVP: central venous pressure; CVS: cardiovascular system; EVLW: extravascular lung water; FFP: fresh frozen plasma; HA: human albumin; Hb: haemoglobin; HES: hydroxyethyl starch; HMW: high molecular weight; ICU: intensive care unit; ITBVI: intrathoracic blood volume index; ITT: intention to treat; IV: intravenous; LMW: low molecular weight; LVEDP: left ventricular end diastolic pressure; MMW: medium molecular weight; MAP: mean arterial pressure; MFG: modified fluid gelatin; MI: myocardial infarction; NSAID: non‐steroidal anti‐inflammatory drug; NYHA: New York Heart Association; PAWP: pulmonary artery wedge pressure; PAOP: pulmonary artery occlusion pressure; PCWP: pulmonary capillary wedge pressure; PPF: plasma protein fraction; PRBC: packed red blood cell; PT: prothrombin time; RBC: red blood cell; RL: Ringer's lactate; SBP: systolic blood pressure; WP: wedge pressure.