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. 2019 Sep 8;40(2):683–708. doi: 10.1002/med.21633

Figure 7.

Figure 7

Concentration dependent dissociation modulation by amiloride and its analogs of [3H]spiperone binding at the dopamine D2 receptor after 20 minutes. (Δ‐amiloride, ▲‐benzamil, ○‐DMA, ●‐EIA, □‐MIBA, ■‐HMA). Amiloride modulates dissociation the least, whereas HMA and MIBA are the most effective modulators of dissociation. Reproduced with permission from Hoare and Strange.53 DMA, 5‐(N,N‐dimethyl)amiloride; EIA, 5‐(N‐ethyl‐N‐isopropyl)amiloride; HMA, 5‐(N,N‐hexamethylene)amiloride; MIBA, 5‐(N‐methyl‐N‐isobutyl)amiloride