Table 2.

Activin‐A modulated miRNAs that are predicted to target genes involved in TGF‐β signaling pathway (DIANA miRpath v3; p < .01)

	Time after Activin‐A pulse	KEGG pathway	p value	# Involved miRNAs	# Involved genes
miRNAs unique and upregulated in A‐OBs	4 hr	TGFβ signaling	1.54 × 10−5	9(/15)	35
miRNAs absent and downregulated in A‐OBs			5.30 × 10−5	8(/15)	29
miRNAs unique and upregulated in A‐OBs	1 day		1.15 × 10−4	8(/19)	17
miRNAs absent and downregulated in A‐OBs			2.70 × 10−2	5(/9)	19

Abbreviations: A‐OBs, Activin‐A treated osteoblasts; KEGG, Kyoto Encyclopedia of Genes and Genomes; miRNAs, microRNAs; TGF‐β, transforming growth factor‐β.