Table 2.
Multivariate analysis of survival using a Cox regression model
| Whole cohort (n = 141) | ||||
|---|---|---|---|---|
| Progression‐free survival | Overall survival | |||
| Parameter | OR (95% CI) | p‐value | OR (95% CI) | p‐value |
| RIG‐I | 1.499 (0.916–2.455) | 0.107 | 2.102 (1.265–3.492) | 0.004 |
| Age1 | – | – | 2.593 (1.653–4.067) | <0.001 |
| FIGO stage2 | 1.347 (0.560–3.240) | 0.505 | 1.065 (0.541–2.095) | 0.855 |
| Grade3 | 1.549 (0.976–2.456) | 0.063 | 1.373 (0.909–2.075) | 0.132 |
| Residual disease4 | 3.240 (1.588–6.610) | 0.001 | 2.608 (1.430–4.755) | 0.002 |
| Cancer type5 | 1.747 (1.063–2.870) | 0.028 | – | – |
| Type‐II cancers (n = 77) | ||||
|---|---|---|---|---|
| Progression‐free survival | Overall survival | |||
| Parameter | OR (95% CI) | p‐value | OR (95% CI) | p‐value |
| RIG‐I | 1.819 (0.998–3.315) | 0.051 | 2.025 (1.101–3.722) | 0.023 |
| Age | – | – | 2.365 (1.300–4.305) | 0.005 |
| FIGO stage | 0.847 (0.278–2.581) | 0.770 | 0.927 (0.318–2.709) | 0.891 |
| Grade | 1.154 (0.668–1.993) | 0.607 | 1.288 (0.742–2.236) | 0.369 |
| Residual disease | 3.389 (1.382–8.310) | 0.008 | 3.209 (1.333–7.726) | 0.009 |
Bold p‐values refer to statistically significant (p < 0.05) results.
Age (<median vs. >median). Age was not statistically significant in univariate analysis of progression‐free survival (p = 0.837), and was therefore not considered in the Cox regression model.
FIGO stage (I/II vs. III/IV).
Grade (G1/G2 vs. G3).
Residual disease (YES vs. NO).
Cancer type (Type‐I vs. Type‐II). Cancer type was not statistically significant in univariate analysis of overall survival (p = 0.277), and was therefore not considered in the Cox regression model.
Abbreviations: CI, confidence interval; FIGO, Fédération Internationale de Gynécologie et d'Obstetrique; OR, odds ratio; RIG‐I, retinoic acid‐inducible gene‐I.