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. 2020 Feb 18;15(2):e0229152. doi: 10.1371/journal.pone.0229152

Table 1. Comparison by gender.

Women N = 31 Men N = 29 P
Age, years 59 [57–64] 59 [55–63] 0.389
Cardiovascular risk factors
 Smoking habit, n (%) 2 (7%) 7 (24%) 0.076
 Hypertension, n (%) 13 (42%) 19 (66%) 0.077
 Dyslipidemia, n (%) 12 (39%) 10 (35%) 0.793
Anthropometric mesures
 BMI, kg/m2 33 [3235] 35 [32–37] 0.149
 Waist circumference, cm 103 [97–106] 120 [109–124] <0.001
Body composition
 Fat mass, % 51 [47–54] 41 [35–44] <0.001
 Fat free mass, % 49 [46–53] 59 [56–65] <0.001
 Fat/free fat ratio 1.03 [0.88–1.15] 0.71 [0.54–0.80] <0.001
 Fat mass index, kg/m2 16.3 [15.3–18.9] 14.6 [10.9–16.7] <0.001
 Fat-free mass index, kg/m2 16.6 [15.8–17.6] 21.0 [19.2–21.8] <0.001
Vital signs
 Systolic blood pressure, mmHg 110 [105–120] 120 [113–130] 0.010
 Diastolic blood pressure, mmHg 70 [60–70] 70 [70–80] 0.008
 Heart rate, beat/min 60 [56–68] 62 [55–69] 0.930
Creatinine, mg/dl 0.74 [0.65–0.79] 1.00 [0.85–1.07] <0.001
Lipid profile
 Total cholesterol, mg/dl 214 [188–241] 190 [180–216] 0.028
 HDL cholesterol, mg/dl 56 [51–65] 44 [38–51] <0.001
 LDL cholesterol, mg/dl 133 [113–150] 120 [108–144] 0.204
 Triglycerides, mg/dl 100 [81–121] 110 [84–145] 0.391
Glucose profile
 Glucose, mg/dl 95 [90–110] 98 [95–107] 0.662
 Glycated Hemoglobin, mmol/mol 37 [35–41] 36 [35–39] 0.334
 Insulin, μU/ml 11.8 [7.8–18.8] 13.8 [10.1–21.0] 0.325
 HOMA Index 2.53 [1.80–5.11] 3.41 [2.37–5.53] 0.348
HOMA index class 0.366
 <2.5 14 (45%) 8 (28%)
 2.5–3.8 6 (19%) 7 (24%)
 >3.8 11 (36%) 14 (48%)
AGE score 2.23 [2.10–2.50] 2.25 [2.05–2.60] 0.918
FINDRISC 14 [1217] 14 [1217] 0.817
FLI 64 [55–77] 92 [79–94] <0.001
Irisin, ng/ml 161 [105–198] 83 [33–115] <0.001

Data are expressed as number (%) and median and interquartiles [I-III].

AGE, Advanced Glycation End-products; BMI, Body Mass Index; FLI, Fatty Liver Index; FINDRISC, Finnish Diabetes Risk Score; HDL, High-Density Lipoprotein; LDL, Low-Density Lipoprotein; HOMA, Homeostasis Model Assessment.