Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of sEH activity by TPPU in liver S-9 fractions from various species.
| Species | IC50 (nM)a |
|---|---|
| Human (male) | 45 ± 3 |
| Monkey (male Cynomolgus) | 16 ± 2 |
| Mouse (male C57BL/6) | 90 ± 5 |
| Rat (male Sprague Dawley) | 41 ± 3 |
| Dog (male Beagle) | 1800 ± 300 |
| Mini pig (male Yutacan) | 220 ± 40 |
IC50 was determined with t-DPPO as a substrate. Results were the average ± SD (n =3).
